作者按时间顺序介绍了古罗马在文艺复兴时间的艺术家和赞助人的故事，以及这座当时最具国际化城市产生的非凡艺术作品。

John Marciari tells the story of the monuments, artists, and patrons of Renaissance Rome in this compelling book. In no other city is the ancient world so palpably present, and nowhere else is the mission of the church so evident. At the same time as the humanists sought to preserve and recreate the ancient city, giving it a new lease on life, the popes dispensed patronage much as any other contemporary Italian ruler.

Rome was also the most international of the Renaissance cities with artists and architects generally training elsewhere before arriving in the city and introducing new trends.

By adopting a chronological structure, covering the period c.1300–1600, Marciari is able to explore the nature of Roman patronage as it differed from papacy to papacy. He examines the city's extraordinary works of art in the context of the working practices, competition, and rivalries that made Renaissance Rome so magnificent.